|
gptkbp:instanceOf
|
gptkb:protein
|
|
gptkbp:crystalStructureAvailable
|
yes
|
|
gptkbp:discoveredBy
|
gptkb:Sandra_L._Schmid
|
|
gptkbp:encodedBy
|
gptkb:DNM1_gene
|
|
gptkbp:foundIn
|
eukaryotic cells
|
|
gptkbp:function
|
GTPase activity
membrane fission
|
|
gptkbp:hasIsoform
|
dynamin-1
dynamin-2
dynamin-3
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
dynamin
|
|
gptkbp:interactsWith
|
gptkb:clathrin
gptkb:amphiphysin
gptkb:endophilin
synaptojanin
|
|
gptkbp:involvedIn
|
vesicle trafficking
endocytosis
|
|
gptkbp:locale
|
gptkb:cytoplasm
gptkb:plasma_membrane
|
|
gptkbp:molecularWeight
|
~100 kDa
|
|
gptkbp:mutationAssociatedWith
|
gptkb:Charcot-Marie-Tooth_disease
gptkb:centronuclear_myopathy
|
|
gptkbp:orthologIn
|
Drosophila shibire protein
|
|
gptkbp:regulates
|
synaptic vesicle recycling
|
|
gptkbp:reviewedBy
|
gptkb:NCBI_Gene
gptkb:UniProt
|
|
gptkbp:structure
|
contains PH domain
contains GTPase domain
contains GED domain
contains PRD domain
|
|
gptkbp:bfsParent
|
gptkb:clathrin
gptkb:SNX9
gptkb:amphiphysin
gptkb:dynamin_superfamily
gptkb:endophilin
gptkb:syndapin
|
|
gptkbp:bfsLayer
|
7
|