Statements (32)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:protein
transcription factor |
| gptkbp:alsoKnownAs |
CBF1/Su(H)/Lag-1 transcription factor
|
| gptkbp:binds |
gptkb:gene
co-activators co-repressors Notch intracellular domain |
| gptkbp:discoveredIn |
1990s
|
| gptkbp:domain |
Rel homology domain
beta-trefoil domain |
| gptkbp:foundIn |
animals
|
| gptkbp:function |
DNA binding
transcriptional regulation |
| gptkbp:gene |
gptkb:RBPJ
CBF1 Lag-1 Su(H) |
| https://www.w3.org/2000/01/rdf-schema#label |
CSL transcription factor
|
| gptkbp:involvedIn |
gptkb:Notch_signaling_pathway
|
| gptkbp:orthologIn |
Lag-1 (C. elegans)
RBPJ (human) Su(H) (Drosophila) |
| gptkbp:PDB |
3BRG
|
| gptkbp:regulates |
cell differentiation
cell fate determination developmental processes Notch target genes |
| gptkbp:requires |
Notch-mediated transcription
|
| gptkbp:structure |
contains three domains: NTD, BTD, CTD
|
| gptkbp:UniProtID |
Q06330
|
| gptkbp:bfsParent |
gptkb:Notch_signaling_pathway
|
| gptkbp:bfsLayer |
7
|