|
gptkbp:instanceOf
|
gptkb:chemical_compound
|
|
gptkbp:approvalYear
|
1899
|
|
gptkbp:ATCCode
|
gptkb:N02BA01
B01AC06
|
|
gptkbp:bioavailability
|
80-100%
|
|
gptkbp:CASNumber
|
50-78-2
|
|
gptkbp:contains
|
many over-the-counter medications
|
|
gptkbp:contraindication
|
children with viral infections
patients with bleeding disorders
hypersensitivity to NSAIDs
patients with peptic ulcer
|
|
gptkbp:drugClass
|
gptkb:Antiplatelet_agent
analgesic
Antipyretic
nonsteroidal anti-inflammatory drug
|
|
gptkbp:eliminationHalfLife
|
2-3 hours
|
|
gptkbp:excretion
|
renal
|
|
gptkbp:hasInChIKey
|
BSYNRYMUTXBXSQ-UHFFFAOYSA-N
|
|
gptkbp:hasMolecularFormula
|
C9H8O4
|
|
gptkbp:hasSMILES
|
CC(=O)Oc1ccccc1C(=O)O
|
|
gptkbp:hasUNII
|
R16CO5Y76E
|
|
gptkbp:hasWikipediaPage
|
gptkb:Aspirin
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
CHEMBL92
|
|
gptkbp:indication
|
fever
pain
inflammation
prevention of cardiovascular events
|
|
gptkbp:isApprovedDrug
|
true
|
|
gptkbp:IUPACName
|
2-acetoxybenzoic acid
|
|
gptkbp:KEGGID
|
D00109
|
|
gptkbp:legalStatus
|
off-patent
|
|
gptkbp:marketedAs
|
gptkb:Bayer
|
|
gptkbp:MeSH_ID
|
D001241
|
|
gptkbp:metabolism
|
liver
|
|
gptkbp:molecularWeight
|
180.16
|
|
gptkbp:name
|
gptkb:Aspirin
|
|
gptkbp:PubChem_CID
|
2244
DB00945
15365
|
|
gptkbp:routeOfAdministration
|
oral
intravenous
rectal
|
|
gptkbp:sideEffect
|
gptkb:Reye's_syndrome_(in_children)
gastrointestinal bleeding
allergic reaction
ulcer
|
|
gptkbp:synonym
|
gptkb:ASA
gptkb:Acetylsalicylic_acid
|
|
gptkbp:target
|
Cyclooxygenase-1 (COX-1)
Cyclooxygenase-2 (COX-2)
|
|
gptkbp:bfsParent
|
gptkb:taxol
|
|
gptkbp:bfsLayer
|
5
|