Statements (30)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:protein
|
| gptkbp:alternativeName |
calcitonin gene-related peptide receptor
|
| gptkbp:encodedBy |
CALCRL gene
|
| gptkbp:enemyOf |
gptkb:fremanezumab
gptkb:erenumab gptkb:galcanezumab rimegepant atogepant ubrogepant |
| gptkbp:expressedIn |
central nervous system
peripheral nervous system vascular smooth muscle |
| gptkbp:function |
G protein-coupled receptor activity
|
| https://www.w3.org/2000/01/rdf-schema#label |
CGRP receptor
|
| gptkbp:involvedIn |
pain transmission
|
| gptkbp:ligand |
gptkb:calcitonin_gene-related_peptide
|
| gptkbp:locatedIn |
gptkb:cell_membrane
|
| gptkbp:medium |
vasodilation
|
| gptkbp:modulatedBy |
vascular tone
neurogenic inflammation |
| gptkbp:requires |
RAMP1 for function
|
| gptkbp:species |
gptkb:Mus_musculus
gptkb:Homo_sapiens |
| gptkbp:subunit |
RAMP1
CALCRL |
| gptkbp:target |
migraine therapeutics
|
| gptkbp:type |
gptkb:cAMP_pathway
|
| gptkbp:bfsParent |
gptkb:RAMP
gptkb:calcitonin_gene-related_peptide_(CGRP) |
| gptkbp:bfsLayer |
7
|