calcitonin gene-related peptide (CGRP)
GPTKB entity
Statements (30)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
peptide
|
| gptkbp:abbreviation |
gptkb:CGRP
|
| gptkbp:alternativeSplicing |
gptkb:CALCA_gene
|
| gptkbp:aminoAcidLength |
37
|
| gptkbp:associatedWith |
migraine
|
| gptkbp:discoveredIn |
1982
|
| gptkbp:encodedBy |
gptkb:CALCA_gene
|
| gptkbp:foundIn |
central nervous system
peripheral nervous system |
| gptkbp:function |
vasodilation
pain transmission |
| gptkbp:halfLife |
7-10 minutes
|
| gptkbp:hasIsoform |
gptkb:alpha-CGRP
gptkb:beta-CGRP |
| https://www.w3.org/2000/01/rdf-schema#label |
calcitonin gene-related peptide (CGRP)
|
| gptkbp:improves |
cAMP levels
|
| gptkbp:inhibitedBy |
smooth muscle contraction
|
| gptkbp:involvedIn |
cardiovascular regulation
neurogenic inflammation |
| gptkbp:receptorComplex |
gptkb:calcitonin_receptor-like_receptor_(CLR)_and_RAMP1
|
| gptkbp:recipient |
gptkb:CGRP_receptor
|
| gptkbp:relatedTo |
gptkb:calcitonin
gptkb:adrenomedullin |
| gptkbp:structure |
peptide
|
| gptkbp:target |
monoclonal antibodies for migraine
|
| gptkbp:UniProtID |
P06881
|
| gptkbp:bfsParent |
gptkb:CALCA_gene
gptkb:Emgality gptkb:Ajovy |
| gptkbp:bfsLayer |
6
|