|
gptkbp:instanceOf
|
gptkb:gene
|
|
gptkbp:alternativeName
|
carboxylesterase 1A
hCE-1
serum carboxylesterase
|
|
gptkbp:associatedWith
|
clopidogrel metabolism
cocaine metabolism
methylphenidate metabolism
oseltamivir metabolism
|
|
gptkbp:biologicalProcess
|
lipid metabolism
xenobiotic metabolic process
carboxylic ester hydrolase activity
|
|
gptkbp:encodes
|
gptkb:carboxylesterase_1
|
|
gptkbp:Entrez_Gene_ID
|
1066
|
|
gptkbp:enzymeCommissionNumber
|
gptkb:EC_3.1.1.1
|
|
gptkbp:expressedIn
|
gptkb:cancer
liver
intestine
|
|
gptkbp:function
|
hydrolyzes ester and amide bonds
|
|
gptkbp:geneType
|
protein-coding
|
|
gptkbp:hasPolymorphism
|
drug response
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
CES1
|
|
gptkbp:involvedIn
|
drug metabolism
|
|
gptkbp:locatedOnChromosome
|
16q13-q22.1
|
|
gptkbp:organism
|
gptkb:Homo_sapiens
|
|
gptkbp:orthologInMouse
|
Ces1
|
|
gptkbp:proteinFamily
|
serine esterase
|
|
gptkbp:subcellularLocation
|
gptkb:endoplasmic_reticulum
microsome
|
|
gptkbp:UniProtID
|
P23141
|
|
gptkbp:bfsParent
|
gptkb:carboxylesterase_family
gptkb:carboxylesterase_1
|
|
gptkbp:bfsLayer
|
8
|