Statements (25)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:protein
|
| gptkbp:component |
gptkb:T-cell_receptor-CD3_complex
|
| gptkbp:domain |
gptkb:ITAM_(immunoreceptor_tyrosine-based_activation_motif)
immunoglobulin-like domain |
| gptkbp:encodedBy |
gptkb:CD3E_gene
|
| gptkbp:foundIn |
gptkb:T_cells
|
| gptkbp:function |
signal transduction in T cells
|
| https://www.w3.org/2000/01/rdf-schema#label |
CD3ε
|
| gptkbp:interactsWith |
gptkb:CD3γ
gptkb:CD3δ gptkb:CD3ζ gptkb:TCR_alpha_chain gptkb:TCR_beta_chain |
| gptkbp:locatedOnChromosome |
gptkb:chromosome_11_(human)
|
| gptkbp:location |
gptkb:cell_membrane
|
| gptkbp:mutationAssociatedWith |
immunodeficiency
|
| gptkbp:OMIM |
186830
|
| gptkbp:requires |
T cell development
|
| gptkbp:target |
gptkb:therapeutic_antibodies_(e.g.,_OKT3)
|
| gptkbp:UniProtID |
P07766
|
| gptkbp:usedAs |
immunohistochemical marker for T cells
|
| gptkbp:bfsParent |
gptkb:T_cell_receptor_complex
gptkb:T-cell_receptor_complex gptkb:CD3_complex |
| gptkbp:bfsLayer |
7
|