Statements (48)
Predicate | Object |
---|---|
gptkbp:instanceOf |
gptkb:gene
|
gptkbp:alternativeName |
MGC22112
PETA-3 SFA-1 TSPAN24 |
gptkbp:associatedWith |
cancer progression
nephrotic syndrome |
gptkbp:discoveredBy |
Molecular cloning studies
|
gptkbp:encodes |
CD151 protein
|
gptkbp:Entrez_Gene_ID |
977
ENSG00000177697 |
gptkbp:expressedIn |
various tissues
|
gptkbp:firstDescribed |
1996
|
gptkbp:function |
signal transduction
cell migration cell adhesion protein binding integrin binding cell adhesion molecule binding |
https://www.w3.org/2000/01/rdf-schema#label |
CD151 gene
|
gptkbp:interactsWith |
gptkb:CD63
gptkb:CD9 gptkb:integrins gptkb:CD81 |
gptkbp:locatedOnChromosome |
gptkb:11p15.5
chromosome 11 |
gptkbp:memberOf |
tetraspanin family
|
gptkbp:mutationAssociatedWith |
renal failure
skin blistering |
gptkbp:OMIM |
602243
|
gptkbp:organism |
gptkb:Homo_sapiens
|
gptkbp:orthologIn |
gptkb:mouse
gptkb:zebrafish right |
gptkbp:pathway |
cell junction organization
integrin-mediated signaling pathway cell surface interactions at the vascular wall |
gptkbp:product |
cell surface receptor
four transmembrane domains CD151 antigen |
gptkbp:significance |
biomarker for cancer
target for therapeutic intervention |
gptkbp:subcellularLocation |
gptkb:plasma_membrane
cell surface extracellular exosome |
gptkbp:UniProtID |
P48509
|
gptkbp:bfsParent |
gptkb:TAPA-1
|
gptkbp:bfsLayer |
8
|