CCL2 gene

GPTKB entity

Statements (34)
Predicate Object
gptkbp:instanceOf gptkb:gene
gptkbp:alsoKnownAs gptkb:MCP-1
gptkbp:associatedWith gptkb:cancer
multiple sclerosis
atherosclerosis
inflammation
rheumatoid arthritis
gptkbp:chromosomeArm gptkb:17q12
gptkbp:discoveredIn 1989
gptkbp:encodes CCL2 protein
gptkbp:Entrez_Gene_ID 6347
ENSG00000108691
gptkbp:expressedIn endothelial cells
fibroblasts
monocytes
smooth muscle cells
gptkbp:function chemokine activity
monocyte chemotaxis
gptkbp:geneType protein-coding
gptkbp:hasTranscriptVariant multiple
https://www.w3.org/2000/01/rdf-schema#label CCL2 gene
gptkbp:length 3 exons
gptkbp:locatedOnChromosome 17
gptkbp:organism gptkb:Homo_sapiens
gptkbp:orthologIn Mus musculus (mouse)
Rattus norvegicus (rat)
gptkbp:proteinFamily CC chemokine family
gptkbp:regulates gptkb:NF-kappaB
cytokines
oxidative stress
immune cell migration
gptkbp:UniProtID P13500
gptkbp:bfsParent gptkb:CC2
gptkbp:bfsLayer 7