C-X-C chemokine receptor type 4 protein
GPTKB entity
Statements (26)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:protein
|
| gptkbp:alsoKnownAs |
gptkb:CXCR4
|
| gptkbp:associatedWith |
gptkb:WHIM_syndrome
cancer metastasis |
| gptkbp:binds |
stromal cell-derived factor 1 (SDF-1/CXCL12)
|
| gptkbp:encodedBy |
CXCR4 gene
|
| gptkbp:expressedIn |
gptkb:leukocytes
endothelial cells hematopoietic stem cells |
| gptkbp:function |
gptkb:G_protein-coupled_receptor
chemokine receptor |
| https://www.w3.org/2000/01/rdf-schema#label |
C-X-C chemokine receptor type 4 protein
|
| gptkbp:involvedIn |
immune cell trafficking
hematopoiesis HIV entry |
| gptkbp:length |
352
|
| gptkbp:locatedIn |
gptkb:cell_membrane
|
| gptkbp:locatedOnChromosome |
2q22.1
|
| gptkbp:molecularWeight |
~40 kDa
|
| gptkbp:PDB |
3ODU
|
| gptkbp:structure |
seven transmembrane domains
|
| gptkbp:target |
gptkb:AMD3100
gptkb:plerixafor |
| gptkbp:UniProtID |
P61073
|
| gptkbp:bfsParent |
gptkb:CXCR4
|
| gptkbp:bfsLayer |
7
|