WHIM syndrome

GPTKB entity

Statements (23)
Predicate Object
gptkbp:instanceOf gptkb:immunodeficiency
gptkb:rare_disease
gptkbp:abbreviation Warts, Hypogammaglobulinemia, Infections, Myelokathexis syndrome
gptkbp:affects immune system
gptkbp:complication recurrent bacterial infections
chronic neutropenia
gptkbp:firstDescribed 1964
gptkbp:frequency very rare
gptkbp:hasGeneticCause mutation in CXCR4 gene
gptkbp:hasOrphanetID gptkb:ORPHA:324
gptkbp:ICD-10_code D80.8
gptkbp:inheritance autosomal dominant
gptkbp:OMIM 193670
gptkbp:symptom infections
warts
hypogammaglobulinemia
myelokathexis
gptkbp:treatment gptkb:plerixafor
immunoglobulin replacement therapy
G-CSF
gptkbp:bfsParent gptkb:mavorixafor
gptkbp:bfsLayer 7
https://www.w3.org/2000/01/rdf-schema#label WHIM syndrome