|
gptkbp:instanceOf
|
gptkb:protein
cytokine
|
|
gptkbp:alsoKnownAs
|
gptkb:MCP-1
Monocyte Chemoattractant Protein 1
|
|
gptkbp:discoveredBy
|
R. J. Nelson et al.
|
|
gptkbp:discoveredIn
|
1989
|
|
gptkbp:encodedBy
|
gptkb:CCL2_gene
|
|
gptkbp:Entrez_Gene_ID
|
6347
ENSG00000108691
|
|
gptkbp:expressedIn
|
gptkb:cancer
gptkb:kidney
brain
heart
liver
lymph nodes
spleen
|
|
gptkbp:foundIn
|
gptkb:Homo_sapiens
|
|
gptkbp:function
|
involved in inflammatory response
chemoattractant for monocytes
|
|
gptkbp:GO
|
gptkb:GO:0006955_(immune_response)
gptkb:GO:0008009_(chemokine_activity)
GO:0006954 (inflammatory response)
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
C-C motif chemokine 2
|
|
gptkbp:involvedIn
|
atherosclerosis
rheumatoid arthritis
cancer metastasis
|
|
gptkbp:length
|
99 amino acids
|
|
gptkbp:locatedOnChromosome
|
gptkb:17q12
|
|
gptkbp:molecularWeight
|
11 kDa
|
|
gptkbp:OMIM
|
158105
|
|
gptkbp:orthologIn
|
Mus musculus (mouse)
Rattus norvegicus (rat)
|
|
gptkbp:PDB
|
1DOK
|
|
gptkbp:recipient
|
gptkb:CCR4
CCR2
|
|
gptkbp:secretes
|
endothelial cells
fibroblasts
monocytes
|
|
gptkbp:structure
|
contains two adjacent cysteines (CC motif)
|
|
gptkbp:UniProtID
|
P13500
|
|
gptkbp:bfsParent
|
gptkb:CC2
|
|
gptkbp:bfsLayer
|
7
|