|
gptkbp:instanceOf
|
gptkb:drug
|
|
gptkbp:ATCCode
|
gptkb:N05BA
|
|
gptkbp:broadcastOn
|
Schedule IV (US)
|
|
gptkbp:cause
|
gptkb:Ataxia
Depression
Confusion
Tolerance
Withdrawal symptoms
Memory impairment
Paradoxical reactions
|
|
gptkbp:chemicalFormula
|
Benzene ring fused to diazepine ring
|
|
gptkbp:contraindication
|
gptkb:Acute_narrow-angle_glaucoma
gptkb:Myasthenia_gravis
Severe respiratory insufficiency
Sleep apnea syndrome
|
|
gptkbp:discoveredIn
|
1950s
|
|
gptkbp:example
|
gptkb:Alprazolam
gptkb:Clonazepam
gptkb:Diazepam
gptkb:Lorazepam
gptkb:Chlordiazepoxide
gptkb:Midazolam
gptkb:Temazepam
|
|
gptkbp:excretion
|
gptkb:Kidneys
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
Benzodiazepine
|
|
gptkbp:interactsWith
|
gptkb:beer
gptkb:Antidepressants
gptkb:Barbiturates
gptkb:Opioids
Antihistamines
Antipsychotics
|
|
gptkbp:legalStatus
|
Prescription only
|
|
gptkbp:marketedAs
|
1960
|
|
gptkbp:mechanismOfAction
|
Enhances GABA-A receptor activity
|
|
gptkbp:metabolism
|
Liver
|
|
gptkbp:overdoseTreatment
|
gptkb:Flumazenil
|
|
gptkbp:pregnancyCategory
|
D (US)
|
|
gptkbp:riskFactor
|
gptkb:Overdose
Addiction
Falls in elderly
Impaired driving
|
|
gptkbp:sideEffect
|
Dizziness
Cognitive impairment
Dependence
Drowsiness
Respiratory depression
|
|
gptkbp:usedFor
|
gptkb:Insomnia
Anxiety disorders
Alcohol withdrawal
Muscle spasms
Seizure disorders
|
|
gptkbp:bfsParent
|
gptkb:D002409
|
|
gptkbp:bfsLayer
|
6
|