Statements (30)
Predicate | Object |
---|---|
gptkbp:instanceOf |
DNA repair mechanism
|
gptkbp:actsOn |
gptkb:gene
|
gptkbp:discoveredBy |
gptkb:Tomas_Lindahl
|
gptkbp:firstDescribed |
1974
|
gptkbp:GO_term |
GO:0006284
|
https://www.w3.org/2000/01/rdf-schema#label |
Base excision repair
|
gptkbp:involvesEnzyme |
gptkb:AP_endonuclease
gptkb:DNA_ligase gptkb:DNA_glycosylase gptkb:DNA_polymerase_beta |
gptkbp:occurredIn |
prokaryotes
eukaryotes |
gptkbp:prevention |
gptkb:cancer
mutagenesis |
gptkbp:relatedTo |
mismatch repair
nucleotide excision repair |
gptkbp:repairs |
oxidative DNA damage
alkylation damage apurinic/apyrimidinic sites deamination damage small base lesions |
gptkbp:requires |
genome stability
|
gptkbp:step |
ligation
gap filling incision of DNA backbone recognition of damaged base removal of damaged base |
gptkbp:bfsParent |
gptkb:Thymine
gptkb:PARP3 |
gptkbp:bfsLayer |
7
|