Base excision repair

GPTKB entity

Statements (30)
Predicate Object
gptkbp:instanceOf DNA repair mechanism
gptkbp:actsOn gptkb:gene
gptkbp:discoveredBy gptkb:Tomas_Lindahl
gptkbp:firstDescribed 1974
gptkbp:GO_term GO:0006284
https://www.w3.org/2000/01/rdf-schema#label Base excision repair
gptkbp:involvesEnzyme gptkb:AP_endonuclease
gptkb:DNA_ligase
gptkb:DNA_glycosylase
gptkb:DNA_polymerase_beta
gptkbp:occurredIn prokaryotes
eukaryotes
gptkbp:prevention gptkb:cancer
mutagenesis
gptkbp:relatedTo mismatch repair
nucleotide excision repair
gptkbp:repairs oxidative DNA damage
alkylation damage
apurinic/apyrimidinic sites
deamination damage
small base lesions
gptkbp:requires genome stability
gptkbp:step ligation
gap filling
incision of DNA backbone
recognition of damaged base
removal of damaged base
gptkbp:bfsParent gptkb:Thymine
gptkb:PARP3
gptkbp:bfsLayer 7