Statements (33)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
DNA repair pathway
|
| gptkbp:abbreviation |
gptkb:BER
|
| gptkbp:actsOn |
damaged DNA bases
|
| gptkbp:discoveredBy |
gptkb:Tomas_Lindahl
|
| gptkbp:discoveredIn |
1974
|
| gptkbp:GO_term |
GO:0006284
|
| https://www.w3.org/2000/01/rdf-schema#label |
Base Excision Repair
|
| gptkbp:involvesEnzyme |
gptkb:AP_endonuclease
gptkb:DNA_ligase gptkb:DNA_polymerase_beta |
| gptkbp:launched |
gptkb:DNA_glycosylase
|
| gptkbp:malfunctionLeadsTo |
neurodegenerative diseases
cancer predisposition |
| gptkbp:occurredIn |
prokaryotes
eukaryotes |
| gptkbp:prevention |
gptkb:cancer
mutagenesis |
| gptkbp:relatedTo |
gptkb:Mismatch_Repair
gptkb:Nucleotide_Excision_Repair |
| gptkbp:removes |
uracil
alkylated bases deaminated bases oxidized bases |
| gptkbp:repairs |
abasic sites
single-base lesions |
| gptkbp:requires |
genome stability
|
| gptkbp:step |
ligation
base removal end processing gap filling incision |
| gptkbp:bfsParent |
gptkb:BER
|
| gptkbp:bfsLayer |
6
|