|
gptkbp:instanceOf
|
gptkb:gene
|
|
gptkbp:alias
|
ATG6
BCL2-interacting coiled-coil protein
|
|
gptkbp:associatedWith
|
autophagy
tumor suppression
|
|
gptkbp:component
|
phagophore assembly site
|
|
gptkbp:discoveredIn
|
1999
|
|
gptkbp:encodes
|
Beclin-1 protein
|
|
gptkbp:Entrez_Gene_ID
|
8678
|
|
gptkbp:expressedIn
|
gptkb:cancer
gptkb:skeletal_muscle
gptkb:kidney
gptkb:placenta
gptkb:prostate
gptkb:testis
brain
heart
liver
various tissues
pancreas
|
|
gptkbp:firstDescribed
|
1999
Liang et al.
|
|
gptkbp:function
|
phosphatidylinositol 3-kinase binding
|
|
gptkbp:GOProcess
|
autophagy
apoptotic process
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
BECN1 gene
|
|
gptkbp:interactsWith
|
gptkb:PIK3C3
gptkb:BCL2_protein
gptkb:UVRAG
AMBRA1
|
|
gptkbp:involvedIn
|
phagophore formation
|
|
gptkbp:length
|
450 amino acids
|
|
gptkbp:locatedOnChromosome
|
gptkb:17q21
|
|
gptkbp:molecularWeight
|
52 kDa
|
|
gptkbp:mutationAssociatedWith
|
gptkb:cancer
prostate cancer
|
|
gptkbp:OMIM
|
601024
|
|
gptkbp:organism
|
gptkb:Homo_sapiens
|
|
gptkbp:orthologIn
|
gptkb:Mus_musculus
gptkb:Caenorhabditis_elegans
gptkb:Drosophila_melanogaster
|
|
gptkbp:proteinFamily
|
Beclin family
|
|
gptkbp:referenceGenome
|
NM_003766
|
|
gptkbp:regulates
|
cell survival
autophagosome formation
cell death
|
|
gptkbp:UniProtID
|
gptkb:Q14457
|
|
gptkbp:bfsParent
|
gptkb:Beclin-1
|
|
gptkbp:bfsLayer
|
6
|