BCL-XL protein

GPTKB entity

Statements (25)
Predicate Object
gptkbp:instanceOf gptkb:protein
gptkbp:alternativeSplicing gptkb:BCL2L1_gene
gptkbp:component mitochondrial outer membrane
gptkbp:encodedBy gptkb:BCL2L1_gene
gptkbp:expressedIn various tissues
gptkbp:function inhibits apoptosis
anti-apoptotic activity
gptkbp:GOProcess regulation of apoptotic process
https://www.w3.org/2000/01/rdf-schema#label BCL-XL protein
gptkbp:interactsWith gptkb:BAD_protein
BAX protein
BAK protein
BID protein
gptkbp:locatedIn mitochondrial outer membrane
gptkbp:memberOf gptkb:Bcl-2_protein_family
gptkbp:molecularWeight ~30 kDa
gptkbp:overexpressedIn gptkb:cancer
gptkbp:PDB gptkb:1R2D
gptkbp:prevention cytochrome c release
gptkbp:regulates mitochondrial membrane permeability
gptkbp:structure contains BH1, BH2, BH3, BH4 domains
gptkbp:target anticancer drugs
gptkbp:UniProtID gptkb:Q07817
gptkbp:bfsParent gptkb:BAD_gene
gptkbp:bfsLayer 7