Statements (50)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:drug
|
| gptkbp:ATCCode |
A04
|
| gptkbp:canBeOverTheCounter |
Yes
|
| gptkbp:canBePrescription |
Yes
|
| gptkbp:contraindication |
Hypersensitivity to drug
|
| https://www.w3.org/2000/01/rdf-schema#label |
Antiemetics
|
| gptkbp:includes |
gptkb:Promethazine
gptkb:Aprepitant gptkb:Dexamethasone gptkb:Dimenhydrinate gptkb:Granisetron gptkb:Metoclopramide gptkb:Ondansetron gptkb:Prochlorperazine gptkb:Scopolamine |
| gptkbp:mechanismOfAction |
Block neurotransmitters involved in vomiting reflex
Dopamine receptor antagonism Histamine receptor antagonism Muscarinic receptor antagonism Serotonin receptor antagonism |
| gptkbp:prescribes |
Physicians
|
| gptkbp:regulates |
Chemoreceptor trigger zone
Vomiting center in medulla |
| gptkbp:routeOfAdministration |
gptkb:Oral
Rectal Intramuscular Intravenous Transdermal |
| gptkbp:sideEffect |
Headache
Constipation Drowsiness Dry mouth Extrapyramidal symptoms |
| gptkbp:usedFor |
Prevention of nausea
Prevention of vomiting |
| gptkbp:usedIn |
gptkb:Vertigo
gptkb:Gastroenteritis gptkb:Motion_sickness Labyrinthitis Alcohol withdrawal Palliative care Chemotherapy-induced nausea Gastrointestinal disorders Migraine-associated nausea Post-anesthesia care Postoperative nausea Pregnancy-related nausea Radiation therapy-induced nausea |
| gptkbp:bfsParent |
gptkb:Nausea
|
| gptkbp:bfsLayer |
5
|