|
gptkbp:instanceOf
|
gptkb:drug
antiemetic
|
|
gptkbp:approvedBy
|
gptkb:European_Union
gptkb:United_States
1991
|
|
gptkbp:ATCCode
|
A04AA02
|
|
gptkbp:availableOn
|
gptkb:tablet
injection
transdermal patch
|
|
gptkbp:brand
|
gptkb:Granisol
gptkb:Kytril
gptkb:Sancuso
|
|
gptkbp:CASNumber
|
109889-09-0
|
|
gptkbp:chemicalClass
|
indazole derivative
|
|
gptkbp:contraindication
|
hypersensitivity to granisetron
|
|
gptkbp:discoveredBy
|
gptkb:Roche
|
|
gptkbp:drugInteraction
|
serotonergic drugs
other 5-HT3 antagonists
|
|
gptkbp:eliminationHalfLife
|
9 hours
|
|
gptkbp:excretion
|
renal
|
|
gptkbp:hasGenericVersion
|
true
|
|
gptkbp:hasMolecularFormula
|
C18H24N4O
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
Granisetron
|
|
gptkbp:KEGGID
|
D00320
|
|
gptkbp:legalStatus
|
prescription only
off-patent
|
|
gptkbp:mechanismOfAction
|
5-HT3 receptor antagonist
|
|
gptkbp:MedlinePlusID
|
a601209
|
|
gptkbp:MeSH_ID
|
D017396
|
|
gptkbp:metabolism
|
hepatic
|
|
gptkbp:molecularWeight
|
312.41 g/mol
|
|
gptkbp:pregnancyCategory
|
B
|
|
gptkbp:PubChem_CID
|
3492
CHEMBL1197
DB00804
|
|
gptkbp:routeOfAdministration
|
oral
subcutaneous
transdermal
intravenous
|
|
gptkbp:sideEffect
|
constipation
dizziness
headache
insomnia
|
|
gptkbp:UNII
|
VL3536305D
|
|
gptkbp:usedFor
|
chemotherapy-induced nausea and vomiting
postoperative nausea and vomiting
radiotherapy-induced nausea and vomiting
prevention of nausea and vomiting
|
|
gptkbp:WHOModelListOfEssentialMedicines
|
true
|
|
gptkbp:bfsParent
|
gptkb:Antiemetics
|
|
gptkbp:bfsLayer
|
6
|