|
gptkbp:instanceOf
|
gptkb:antiemetic
gptkb:drug
|
|
gptkbp:approvedBy
|
1990
|
|
gptkbp:ATCCode
|
gptkb:A04AA01
|
|
gptkbp:brand
|
gptkb:Zofran
gptkb:Emeset
gptkb:Ondemet
|
|
gptkbp:CASNumber
|
99614-02-5
|
|
gptkbp:chemicalClass
|
carbazole derivative
|
|
gptkbp:contraindication
|
hypersensitivity to ondansetron
|
|
gptkbp:discoveredBy
|
GlaxoSmithKline
|
|
gptkbp:eliminationHalfLife
|
3-6 hours
|
|
gptkbp:excretion
|
urine
feces
|
|
gptkbp:form
|
gptkb:tablet
oral solution
solution for injection
oral disintegrating tablet
|
|
gptkbp:genericAvailable
|
yes
|
|
gptkbp:hasMolecularFormula
|
C18H19N3O
|
|
gptkbp:IUPACName
|
9-methyl-3-[(2-methyl-1H-imidazol-1-yl)methyl]-2,3,4,9-tetrahydro-1H-carbazol-4-one
|
|
gptkbp:legalStatus
|
prescription only
|
|
gptkbp:mechanismOfAction
|
gptkb:serotonin_5-HT3_receptor_antagonist
|
|
gptkbp:metabolism
|
liver
|
|
gptkbp:patentExpired
|
2006 (US)
|
|
gptkbp:pregnancyCategory
|
B (US)
B1 (Australia)
|
|
gptkbp:proteinBinding
|
70-76%
|
|
gptkbp:PubChem_CID
|
4595
DB00904
|
|
gptkbp:routeOfAdministration
|
oral
intramuscular
intravenous
sublingual
|
|
gptkbp:sideEffect
|
constipation
dizziness
fatigue
headache
QT prolongation
|
|
gptkbp:synonym
|
gptkb:GR_38032F
|
|
gptkbp:UNII
|
4QWG6N8QKH
|
|
gptkbp:usedFor
|
chemotherapy-induced nausea and vomiting
postoperative nausea and vomiting
radiotherapy-induced nausea and vomiting
prevention of nausea and vomiting
treatment of nausea and vomiting
|
|
gptkbp:WHOModelListOfEssentialMedicines
|
included
|
|
gptkbp:bfsParent
|
gptkb:Antiemetics
|
|
gptkbp:bfsLayer
|
7
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
Ondansetron
|