|
gptkbp:instanceOf
|
gptkb:Aflatoxin
Mycotoxin
|
|
gptkbp:affectsOrgan
|
liver
|
|
gptkbp:biotransformation
|
gptkb:cytochrome_P450_enzymes
|
|
gptkbp:carcinogenicity
|
gptkb:Group_1_(IARC)
|
|
gptkbp:CASNumber
|
1162-65-8
|
|
gptkbp:category
|
Natural product
Food contaminant
Hepatotoxin
|
|
gptkbp:cause
|
liver cancer
aflatoxicosis
|
|
gptkbp:chemicalFormula
|
C17H12O6
|
|
gptkbp:color
|
pale yellow crystals
|
|
gptkbp:detects
|
gptkb:ELISA
gptkb:HPLC
gptkb:TLC
|
|
gptkbp:discoveredBy
|
gptkb:Martin_S._Goldblatt
|
|
gptkbp:discoveredIn
|
1960
|
|
gptkbp:foundIn
|
corn
peanuts
tree nuts
contaminated grains
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
Aflatoxin B1
|
|
gptkbp:LD50
|
0.5–10 mg/kg (varies by species)
|
|
gptkbp:mainToxicMetabolite
|
gptkb:Aflatoxin_B1-8,9-epoxide
|
|
gptkbp:maximumAllowedLevel
|
20 ppb in food (US FDA)
|
|
gptkbp:meltingPoint
|
268–269 °C
|
|
gptkbp:metabolism
|
gptkb:Aflatoxin_M1
|
|
gptkbp:molecularWeight
|
312.27 g/mol
|
|
gptkbp:producedBy
|
gptkb:Aspergillus_parasiticus
gptkb:Aspergillus_flavus
|
|
gptkbp:PubChem_CID
|
186907
CHEBI:27385
|
|
gptkbp:regulates
|
regulated in food by FDA
|
|
gptkbp:relatedTo
|
gptkb:Aflatoxin_B2
gptkb:Aflatoxin_G1
gptkb:Aflatoxin_M1
|
|
gptkbp:riskFactor
|
Carcinogen
high risk in developing countries
|
|
gptkbp:routeOfExposure
|
oral
inhalation
dermal (rare)
|
|
gptkbp:solubility
|
slightly soluble in water
soluble in chloroform
soluble in methanol
|
|
gptkbp:storage
|
protect from light
store at -20°C
|
|
gptkbp:toxicity
|
highly toxic
|
|
gptkbp:UNII
|
H4N913140U
|
|
gptkbp:UVAbsorption
|
max at 223, 265, 362 nm
|
|
gptkbp:bfsParent
|
gptkb:ABF
|
|
gptkbp:bfsLayer
|
6
|