Statements (57)
| Predicate | Object |
|---|---|
| gptkbp:instance_of |
gptkb:Oncology
|
| gptkbp:affects |
adults
|
| gptkbp:associated_with |
immunosuppression
|
| gptkbp:caused_by |
gptkb:HTLV-1_virus
|
| gptkbp:clinical_trial |
gptkb:immunotherapy
gptkb:anemia combination therapy targeted therapy new therapies thrombocytopenia elevated white blood cell count organomegaly |
| gptkbp:condition |
gptkb:myelodysplastic_syndromes
gptkb:Oncology |
| gptkbp:death |
low
high |
| gptkbp:diagnosis |
gptkb:CD_format
blood tests flow cytometry poor CD4 bone marrow biopsy CD25 CD7 |
| gptkbp:discovered_by |
gptkb:1977
|
| gptkbp:epidemiology |
more common in Africa
more common in Caribbean more common in Japan |
| gptkbp:genetic_studies |
gptkb:IL-2_receptor
gptkb:p53 Ras CD4+ T-cells |
| https://www.w3.org/2000/01/rdf-schema#label |
Adult T-cell leukemia
|
| gptkbp:research_focus |
biomarkers
treatment resistance genetic profiling HTLV-1 transmission |
| gptkbp:risk_factor |
age
geographic location family history HTLV-1 infection |
| gptkbp:symptoms |
fatigue
skin lesions hypercalcemia lymphadenopathy |
| gptkbp:treatment |
chemotherapy
relapse remission stem cell transplant overall survival progression-free survival antiviral therapy |
| gptkbp:type |
gptkb:T-cell_neoplasm
|
| gptkbp:type_of |
acute T-cell leukemia
chronic T-cell leukemia |
| gptkbp:bfsParent |
gptkb:HTLV-1_virus
|
| gptkbp:bfsLayer |
5
|