Statements (46)
| Predicate | Object |
|---|---|
| gptkbp:instance_of |
gptkb:blood
|
| gptkbp:affects |
bone marrow
|
| gptkbp:associated_with |
risk of leukemia
|
| gptkbp:characterized_by |
ineffective hematopoiesis
|
| gptkbp:complication |
gptkb:disease
gptkb:Oncology thrombocytopenia bleeding disorders neutropenia |
| gptkbp:diagnosis |
bone marrow biopsy
varies by subtype depends on age depends on overall health depends on cytogenetics |
| gptkbp:epidemiology |
more common in men
incidence increases with age |
| gptkbp:genetic_studies |
gptkb:TP53
gptkb:ASXL1 gptkb:DNMT3_A gptkb:SF3_B1 gptkb:TET2 |
| https://www.w3.org/2000/01/rdf-schema#label |
myelodysplastic syndromes
|
| gptkbp:prevalence |
higher in older adults
|
| gptkbp:research_focus |
biomarkers
clinical trials genetic studies new therapies |
| gptkbp:risk_factor |
age
radiation exposure exposure to chemicals previous chemotherapy |
| gptkbp:scientific_classification |
gptkb:Oncology
gptkb:chronic_myelomonocytic_leukemia refractory anemia |
| gptkbp:symptoms |
gptkb:anemia
fatigue bleeding infections |
| gptkbp:treatment |
growth factors
supportive care chemotherapy immunosuppressive therapy bone marrow transplant hypomethylating agents |
| gptkbp:bfsParent |
gptkb:Oncology
|
| gptkbp:bfsLayer |
4
|