Activin receptor-like kinase 1
GPTKB entity
Statements (27)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:protein
gptkb:enzyme |
| gptkbp:alternativeName |
gptkb:ALK1
gptkb:ACVRL1 |
| gptkbp:biologicalProcess |
angiogenesis
vascular development |
| gptkbp:domain |
extracellular ligand-binding domain
protein kinase domain |
| gptkbp:EC_number |
2.7.11.30
|
| gptkbp:encodedBy |
gptkb:ACVRL1_gene
|
| gptkbp:Entrez_Gene_ID |
gptkb:ACVRL1
|
| gptkbp:foundIn |
humans
other vertebrates |
| gptkbp:function |
serine/threonine kinase activity
mediates TGF-beta signaling |
| gptkbp:HGNC_ID |
172
|
| https://www.w3.org/2000/01/rdf-schema#label |
Activin receptor-like kinase 1
|
| gptkbp:interactsWith |
gptkb:endoglin
TGF-beta ligands |
| gptkbp:locatedOnChromosome |
chromosome 12q13
|
| gptkbp:location |
gptkb:cell_membrane
|
| gptkbp:memberOf |
gptkb:TGF-beta_receptor_family
|
| gptkbp:mutationAssociatedWith |
gptkb:hereditary_hemorrhagic_telangiectasia_type_2
|
| gptkbp:OMIM |
601284
|
| gptkbp:UniProtID |
gptkb:P37023
|
| gptkbp:bfsParent |
gptkb:ALK1
|
| gptkbp:bfsLayer |
7
|