Statements (31)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:gene
|
| gptkbp:alternativeName |
IRP1
|
| gptkbp:associatedWith |
hereditary hyperferritinemia-cataract syndrome
|
| gptkbp:biologicalProcess |
tricarboxylic acid cycle
aconitate hydratase activity iron ion binding cellular iron ion homeostasis |
| gptkbp:cofactor |
4Fe-4S cluster
|
| gptkbp:encodes |
Aconitase 1
|
| gptkbp:Entrez_Gene_ID |
48
ENSG00000087086 |
| gptkbp:expressedIn |
gptkb:kidney
heart liver |
| gptkbp:function |
regulates iron metabolism
catalyzes the isomerization of citrate to isocitrate in the TCA cycle |
| gptkbp:geneType |
protein-coding
|
| gptkbp:HGNC_ID |
HGNC:119
|
| gptkbp:locatedOnChromosome |
9p21.1
|
| gptkbp:OMIM |
103700
|
| gptkbp:organism |
gptkb:Homo_sapiens
|
| gptkbp:orthologInMouse |
Aco1
|
| gptkbp:product |
Aconitase 1, cytoplasmic
|
| gptkbp:regulates |
ferritin mRNA translation
transferrin receptor mRNA stability |
| gptkbp:subcellularLocation |
gptkb:nucleus
gptkb:cytoplasm |
| gptkbp:UniProtID |
gptkb:P21399
|
| gptkbp:bfsParent |
gptkb:Aconitase
|
| gptkbp:bfsLayer |
7
|
| http://www.w3.org/2000/01/rdf-schema#label |
ACO1
|