|
gptkbp:instanceOf
|
gptkb:gene
|
|
gptkbp:alternativeName
|
IRP1
|
|
gptkbp:associatedWith
|
hereditary hyperferritinemia-cataract syndrome
|
|
gptkbp:biologicalProcess
|
tricarboxylic acid cycle
aconitate hydratase activity
iron ion binding
cellular iron ion homeostasis
|
|
gptkbp:cofactor
|
4Fe-4S cluster
|
|
gptkbp:encodes
|
Aconitase 1
|
|
gptkbp:Entrez_Gene_ID
|
48
ENSG00000087086
|
|
gptkbp:expressedIn
|
gptkb:kidney
heart
liver
|
|
gptkbp:function
|
regulates iron metabolism
catalyzes the isomerization of citrate to isocitrate in the TCA cycle
|
|
gptkbp:geneType
|
protein-coding
|
|
gptkbp:HGNC_ID
|
HGNC:119
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
ACO1
|
|
gptkbp:locatedOnChromosome
|
9p21.1
|
|
gptkbp:OMIM
|
103700
|
|
gptkbp:organism
|
gptkb:Homo_sapiens
|
|
gptkbp:orthologInMouse
|
Aco1
|
|
gptkbp:product
|
Aconitase 1, cytoplasmic
|
|
gptkbp:regulates
|
ferritin mRNA translation
transferrin receptor mRNA stability
|
|
gptkbp:subcellularLocation
|
gptkb:nucleus
gptkb:cytoplasm
|
|
gptkbp:UniProtID
|
gptkb:P21399
|
|
gptkbp:bfsParent
|
gptkb:Aconitase
|
|
gptkbp:bfsLayer
|
7
|