Acetyl-CoA acetyltransferase

URI: https://gptkb.org/entity/Acetyl-CoA_acetyltransferase
GPTKB entity
Statements (33)
Predicate Object
gptkbp:instanceOf gptkb:enzyme
gptkbp:alternativeName gptkb:thiolase
acetoacetyl-CoA thiolase
gptkbp:associatedWith beta-ketothiolase deficiency
gptkbp:biologicalProcess acetyl-CoA C-acetyltransferase activity
gptkbp:CASNumber 9014-76-4
gptkbp:catalyzes acetyl-CoA + acetyl-CoA ⇌ CoA + acetoacetyl-CoA
gptkbp:cellularComponent mitochondrial matrix
peroxisomal matrix
gptkbp:cofactor gptkb:Coenzyme_A
gptkbp:EC_number 2.3.1.9
gptkbp:enzymeClassification transferase
gptkbp:foundIn gptkb:peroxisome
mitochondria
gptkbp:gene gptkb:ACAT1
gptkb:ACAT2
gptkbp:GO_term GO:0003985
https://www.w3.org/2000/01/rdf-schema#label Acetyl-CoA acetyltransferase
gptkbp:involves fatty acid metabolism
ketone body metabolism
gptkbp:organism gptkb:Homo_sapiens
gptkb:Bacteria
gptkbp:PDB 2IBW
1AFW
gptkbp:product gptkb:CoA
acetoacetyl-CoA
gptkbp:structure homotetramer
gptkbp:substrate acetyl-CoA
gptkbp:systematicName acetyl-CoA:acetyl-CoA C-acetyltransferase
gptkbp:UniProt_ID_(human_ACAT1) P24752
gptkbp:UniProt_ID_(human_ACAT2) gptkb:Q9BWD1
gptkbp:bfsParent gptkb:ACAT
gptkbp:bfsLayer 8