|
gptkbp:instanceOf
|
gptkb:protein
|
|
gptkbp:alias
|
ATFX
bZIP protein ATF-5
|
|
gptkbp:alternativeSplicing
|
yes
|
|
gptkbp:biologicalProcess
|
cell proliferation
cell survival
transcription regulation
stress response
DNA binding
neural differentiation
|
|
gptkbp:discoveredIn
|
1998
|
|
gptkbp:encodedBy
|
ATF5 gene
|
|
gptkbp:Entrez_Gene_ID
|
22809
ENSG00000126456
|
|
gptkbp:expressedIn
|
gptkb:testis
brain
liver
various tumors
|
|
gptkbp:fullName
|
Activating transcription factor 5
|
|
gptkbp:function
|
transcription factor
|
|
gptkbp:gene
|
gptkb:ATF5
|
|
gptkbp:HGNC_ID
|
HGNC:791
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
ATF5
|
|
gptkbp:interactsWith
|
gptkb:ATF4
gptkb:CREB1
C/EBP family proteins
|
|
gptkbp:locatedOnChromosome
|
gptkb:chromosome_19q13.33
|
|
gptkbp:memberOf
|
gptkb:ATF/CREB_family
|
|
gptkbp:organism
|
gptkb:Homo_sapiens
|
|
gptkbp:orthologIn
|
gptkb:Mus_musculus
gptkb:Rattus_norvegicus
|
|
gptkbp:postTranslationalModification
|
phosphorylation
|
|
gptkbp:significance
|
implicated in glioblastoma
potential cancer therapeutic target
|
|
gptkbp:subcellularLocation
|
gptkb:nucleus
gptkb:cytoplasm
|
|
gptkbp:UniProtID
|
Q9Y2D1
|
|
gptkbp:bfsParent
|
gptkb:ATF_family
|
|
gptkbp:bfsLayer
|
7
|