|
gptkbp:instanceOf
|
gptkb:gene
|
|
gptkbp:alias
|
Arg3.1
activity-regulated cytoskeleton-associated protein
|
|
gptkbp:associatedWith
|
gptkb:Alzheimer's_disease
gptkb:autism_spectrum_disorder
neuropsychiatric disorders
|
|
gptkbp:biologicalProcess
|
gptkb:long-term_potentiation
protein binding
long-term depression
synaptic scaling
|
|
gptkbp:discoveredIn
|
1995
|
|
gptkbp:encodes
|
gptkb:Activity-regulated_cytoskeleton-associated_protein
|
|
gptkbp:Entrez_Gene_ID
|
gptkb:ENSG00000136535
23237
|
|
gptkbp:evolvesFrom
|
retrotransposon-derived
|
|
gptkbp:expressedIn
|
brain
activity-dependent
inducible
|
|
gptkbp:firstDescribed
|
Lyford et al.
|
|
gptkbp:function
|
gptkb:synaptic_plasticity
memory formation
|
|
gptkbp:geneType
|
protein-coding
|
|
gptkbp:HGNC_ID
|
HGNC:651
|
|
gptkbp:length
|
2 exons
|
|
gptkbp:locatedOnChromosome
|
chromosome 8
|
|
gptkbp:mutationAssociatedWith
|
gptkb:intellectual_disability
cognitive impairment
|
|
gptkbp:OMIM
|
611557
|
|
gptkbp:organism
|
gptkb:Homo_sapiens
|
|
gptkbp:orthologInMouse
|
Arc gene (mouse)
|
|
gptkbp:pathway
|
neurotransmitter release
learning and memory
synaptic signaling
|
|
gptkbp:product
|
ARC protein
|
|
gptkbp:proteinFamily
|
coiled-coil domain
capsid-like domain
|
|
gptkbp:regulates
|
neuronal activity
activity-dependent
synaptic strength
AMPA receptor trafficking
|
|
gptkbp:relatedTo
|
synaptic plasticity research
|
|
gptkbp:species
|
gptkb:human
|
|
gptkbp:studiedIn
|
humans
rodents
|
|
gptkbp:subcellularLocation
|
gptkb:nucleus
gptkb:cytoplasm
postsynaptic density
|
|
gptkbp:UniProtID
|
gptkb:Q7LC44
|
|
gptkbp:bfsParent
|
gptkb:Arc_protein
|
|
gptkbp:bfsLayer
|
8
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
ARC gene
|