Statements (70)
| Predicate | Object |
|---|---|
| gptkbp:instance_of |
gptkb:protein
|
| gptkbp:associated_with |
gptkb:psychologist
|
| gptkbp:has_method |
binding to lipoprotein particles
|
| gptkbp:has_role |
cholesterol transport
|
| gptkbp:has_variants |
gptkb:APOE_ε2
gptkb:APOE_ε3 gptkb:APOE_ε4 |
| https://www.w3.org/2000/01/rdf-schema#label |
APOE protein family
|
| gptkbp:includes |
gptkb:Apolipoprotein_E
|
| gptkbp:is_associated_with |
gptkb:psychologist
cognitive decline obesity atherosclerosis neurodegenerative disorders neuroprotective effects chronic diseases risk neurodegeneration risk |
| gptkbp:is_found_in |
gptkb:plasma
human body |
| gptkbp:is_involved_in |
cell signaling
cellular homeostasis cellular metabolism immune response lipid metabolism lipid transport inflammation neuroinflammation cellular signaling pathways neurodegeneration vascular health cellular communication synaptic function protein metabolism cellular repair mechanisms neuronal repair lipid homeostasis |
| gptkbp:is_linked_to |
gptkb:psychologist
metabolic disorders chronic diseases metabolic syndrome cardiovascular diseases chronic inflammation type 2 diabetes cognitive disorders |
| gptkbp:is_part_of |
apolipoprotein family
lipid transport system lipoprotein assembly lipoprotein metabolism pathway |
| gptkbp:is_represented_in |
gptkb:microprocessor
gptkb:skincare_product kidney liver adipose tissue macrophages endothelial cells spleen lung tissue |
| gptkbp:is_studied_in |
clinical trials
therapeutic interventions genetic research genetic predisposition public health research aging research therapeutic targets biomarker research |
| gptkbp:promoter |
gptkb:APOE_gene
|
| gptkbp:regulates |
hormones
|
| gptkbp:targets |
drug development
|
| gptkbp:bfsParent |
gptkb:APOE_ε3
|
| gptkbp:bfsLayer |
8
|