Statements (31)
Predicate | Object |
---|---|
gptkbp:instanceOf |
gptkb:protein
|
gptkbp:associatedWith |
gptkb:Alzheimer's_disease
gptkb:cardiovascular_disease |
gptkbp:binds |
gptkb:heparan_sulfate_proteoglycans
gptkb:LDL_receptor |
gptkbp:discoveredIn |
1973
|
gptkbp:encodedBy |
gptkb:APOE_gene
|
gptkbp:expressedIn |
brain
liver macrophages |
gptkbp:foundIn |
humans
other mammals |
gptkbp:fullName |
gptkb:Apolipoprotein_E
|
gptkbp:function |
cholesterol metabolism
lipid transport |
gptkbp:gene |
gptkb:APOE
|
gptkbp:hasIsoform |
APOE2
APOE3 APOE4 |
https://www.w3.org/2000/01/rdf-schema#label |
APO-E
|
gptkbp:involvedIn |
lipoprotein metabolism
neuronal repair |
gptkbp:locatedOnChromosome |
gptkb:chromosome_19
|
gptkbp:molecularWeight |
34 kDa
|
gptkbp:protectiveAllele |
APOE2
|
gptkbp:riskAllele |
APOE4
|
gptkbp:riskFactor |
gptkb:late-onset_Alzheimer's_disease
|
gptkbp:structure |
299 amino acids
|
gptkbp:UniProtID |
P02649
|
gptkbp:bfsParent |
gptkb:HGNC:175
|
gptkbp:bfsLayer |
7
|