Statements (29)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:protein
|
| gptkbp:activatedBy |
gptkb:caspase-1
IL-18 maturation IL-1β maturation |
| gptkbp:alias |
Absent in melanoma 2 protein
IFI16-like protein Interferon-inducible protein AIM2 |
| gptkbp:associatedWith |
gptkb:cancer
autoimmune diseases |
| gptkbp:discoveredBy |
Ting JP-Y et al.
|
| gptkbp:domain |
PYD domain
HIN-200 domain |
| gptkbp:encodedBy |
AIM2 gene
|
| gptkbp:fullName |
Absent in Melanoma 2
|
| gptkbp:function |
innate immune response
cytosolic DNA sensor inflammasome formation |
| gptkbp:gene |
gptkb:AIM2
|
| https://www.w3.org/2000/01/rdf-schema#label |
AIM2
|
| gptkbp:involvedIn |
apoptosis
pyroptosis |
| gptkbp:locatedOnChromosome |
1q23
|
| gptkbp:location |
gptkb:cytoplasm
|
| gptkbp:organism |
gptkb:Homo_sapiens
|
| gptkbp:orthologIn |
gptkb:Mus_musculus
|
| gptkbp:PDB |
3RN5
|
| gptkbp:UniProtID |
O14862
|
| gptkbp:bfsParent |
gptkb:MNDA
|
| gptkbp:bfsLayer |
7
|