|
gptkbp:instanceOf
|
gptkb:gene
|
|
gptkbp:alternativeName
|
gptkb:AT2_receptor
AT2R
Angiotensin II receptor type-2
|
|
gptkbp:associatedWith
|
cardiovascular system
renal system
blood pressure regulation
AGTR1
|
|
gptkbp:cellularComponent
|
gptkb:plasma_membrane
|
|
gptkbp:discoveredIn
|
1993
|
|
gptkbp:encodes
|
angiotensin II receptor type 2 protein
|
|
gptkbp:enemyOf
|
EMA401
PD123319
|
|
gptkbp:Entrez_Gene_ID
|
186
ENSG00000180772
|
|
gptkbp:expressedIn
|
gptkb:adrenal_gland
gptkb:kidney
brain
heart
uterus
fetal tissues
|
|
gptkbp:fullName
|
angiotensin II receptor type 2
|
|
gptkbp:function
|
gptkb:G_protein-coupled_receptor
mediates effects of angiotensin II
|
|
gptkbp:geneLocationEnd
|
114,090,017
|
|
gptkbp:geneLocationStart
|
114,086,282
|
|
gptkbp:geneType
|
protein-coding
|
|
gptkbp:hasTranscriptVariant
|
NM_000686
|
|
gptkbp:HGNC_ID
|
333
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
AGTR2
|
|
gptkbp:length
|
363
|
|
gptkbp:locatedOnChromosome
|
Xq23
|
|
gptkbp:molecularWeight
|
41 kDa
|
|
gptkbp:mutationAssociatedWith
|
gptkb:X-linked_intellectual_disability
congenital anomalies of kidney and urinary tract
|
|
gptkbp:OMIM
|
300034
|
|
gptkbp:organism
|
gptkb:Homo_sapiens
|
|
gptkbp:orthologInMouse
|
Agtr2
|
|
gptkbp:product
|
NP_000677
|
|
gptkbp:proteinFamily
|
angiotensin receptor family
|
|
gptkbp:receptorFor
|
gptkb:angiotensin_II
|
|
gptkbp:regulates
|
downregulated in adult tissues
upregulated in fetal tissues
|
|
gptkbp:strand
|
reverse
|
|
gptkbp:type
|
induces apoptosis
inhibits cell proliferation
promotes vasodilation
inhibits inflammation
|
|
gptkbp:UniProtID
|
P50052
|
|
gptkbp:bfsParent
|
gptkb:AT2_receptor
|
|
gptkbp:bfsLayer
|
7
|