|
gptkbp:instanceOf
|
gptkb:gene
|
|
gptkbp:alias
|
ADAR1
DRADA
DSRAD
|
|
gptkbp:alternativeSplicing
|
yes
|
|
gptkbp:associatedWith
|
gptkb:ADARB1
gptkb:ADARB2
Aicardi-Goutieres syndrome
ADAD1
ADAD2
|
|
gptkbp:component
|
gptkb:nucleus
|
|
gptkbp:discoveredBy
|
gptkb:Brenda_L._Bass
|
|
gptkbp:discoveredIn
|
1991
|
|
gptkbp:encodes
|
ADAR enzyme
|
|
gptkbp:Entrez_Gene_ID
|
103
ENSG00000160710
|
|
gptkbp:enzymeClassification
|
EC 3.5.4.38
|
|
gptkbp:expressedIn
|
gptkb:cancer
brain
liver
|
|
gptkbp:fullName
|
Adenosine Deaminase Acting on RNA
|
|
gptkbp:function
|
RNA editing
A-to-I editing
RNA editing by deamination
|
|
gptkbp:GOProcess
|
mRNA processing
|
|
gptkbp:hasTranscriptVariant
|
multiple
|
|
gptkbp:HGNC_ID
|
HGNC:186
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
ADAR
|
|
gptkbp:interactsWith
|
gptkb:MDA5
PKR
Z-DNA
dsRNA
|
|
gptkbp:locatedOnChromosome
|
1q21
|
|
gptkbp:molecularWeight
|
~150 kDa
|
|
gptkbp:mutationAssociatedWith
|
autoimmune disease
neurological disorder
|
|
gptkbp:numberOfExons
|
15
|
|
gptkbp:OMIM
|
601484
|
|
gptkbp:organism
|
gptkb:Homo_sapiens
|
|
gptkbp:orthologInMouse
|
gptkb:Adar
|
|
gptkbp:orthologInZebrafish
|
adar
|
|
gptkbp:PDB
|
5ED1
|
|
gptkbp:product
|
ADAR1
p110 isoform
p150 isoform
|
|
gptkbp:proteinFamily
|
deaminase domain
dsRNA binding domain
|
|
gptkbp:referenceGenome
|
gptkb:GRCh38
|
|
gptkbp:RefSeq
|
NM_001111
|
|
gptkbp:regulates
|
interferon-inducible
|
|
gptkbp:subcellularLocation
|
gptkb:nucleus
gptkb:cytoplasm
|
|
gptkbp:UniProtID
|
P55265
|
|
gptkbp:bfsParent
|
gptkb:chromosome_1q21
gptkb:Adenosine_deaminase_acting_on_RNA
|
|
gptkbp:bfsLayer
|
7
|