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gptkbp:instanceOf
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gptkb:protein
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gptkbp:alsoKnownAs
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gptkb:ATPases_Associated_with_diverse_cellular_Activities
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gptkbp:associatedWith
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gptkb:cancer
gptkb:muscular_dystrophy
gptkb:cardiomyopathy
neurodegenerative diseases
inherited ataxias
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gptkbp:database
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InterPro: IPR003593
PROSITE: PS00674
Pfam: PF00004
SCOP: 1e32
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gptkbp:domain
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gptkb:AAA_domain
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gptkbp:evolvesFrom
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gptkb:P-loop_NTPase_superfamily
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gptkbp:firstDescribed
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1990s
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gptkbp:foundIn
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gptkb:Bacteria
archaea
eukaryotes
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gptkbp:function
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DNA replication
protein degradation
protein unfolding
membrane fusion
protein disaggregation
ATP hydrolysis
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gptkbp:involvedIn
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DNA repair
cell cycle regulation
mitochondrial function
vesicle trafficking
protein quality control
cellular homeostasis
cytoskeletal organization
organelle biogenesis
chromatin remodeling
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gptkbp:motif
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gptkb:Walker_A_motif
gptkb:Walker_B_motif
gptkb:arginine_finger
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gptkbp:powerSource
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gptkb:ATP
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gptkbp:regulates
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gptkb:histone_modification
nucleotide binding
cofactor interaction
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gptkbp:structure
|
hexameric ring
oligomeric complex
|
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gptkbp:superfamily
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gptkb:NSF
gptkb:Clp_protease
gptkb:dynein
gptkb:p97/VCP
gptkb:Hsp104
MCM helicase
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gptkbp:bfsParent
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gptkb:AAA_domain
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gptkbp:bfsLayer
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7
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https://www.w3.org/2000/01/rdf-schema#label
|
AAA+ ATPase proteins
|