Statements (55)
Predicate | Object |
---|---|
gptkbp:instance_of |
gptkb:protein
|
gptkbp:associated_with |
gptkb:diabetes
gptkb:Oncology gptkb:neurodegenerative_diseases autoimmune diseases inflammation metabolic syndrome obesity liver disease cardiovascular diseases chronic kidney disease infectious diseases pulmonary diseases |
gptkbp:clinical_trial |
biomarker for disease
|
gptkbp:function |
inhibitor of proteases
|
https://www.w3.org/2000/01/rdf-schema#label |
A2 M
|
gptkbp:initiated_by |
gptkb:matrix_metalloproteinases
thrombin trypsin plasmin |
gptkbp:interacts_with |
various proteases
|
gptkbp:involved_in |
apoptosis
cell proliferation cell signaling cellular homeostasis cellular stress response immune response signal transduction wound healing neuroinflammation oxidative stress response angiogenesis chronic inflammation immune cell activation inflammatory response tissue repair neuroprotection cell migration metabolism of lipids tumor progression extracellular matrix regulation tissue remodeling immune evasion fibrinolysis tumor metastasis metabolism of carbohydrates metabolism of proteins |
gptkbp:location |
gptkb:plasma
|
gptkbp:produced_by |
liver
|
gptkbp:promoter |
gptkb:A2_M_gene
|
gptkbp:role |
transport of growth factors
|
gptkbp:weight |
approximately 720 k Da
|
gptkbp:bfsParent |
gptkb:X-Men:_Rise_of_the_Mutants
gptkb:Pirates_of_the_Caribbean:_Dead_Man's_Chest |
gptkbp:bfsLayer |
5
|