Statements (53)
| Predicate | Object |
|---|---|
| gptkbp:instance_of |
gptkb:physicist
|
| gptkbp:bfsLayer |
5
|
| gptkbp:bfsParent |
gptkb:A2_M
|
| gptkbp:application |
studied in cancer research
|
| gptkbp:associated_with |
inflammatory response
|
| gptkbp:clinical_trial |
studied for therapeutic targets
biomarker for certain diseases involved in clinical trials for therapies |
| gptkbp:code |
alpha-2-macroglobulin protein
|
| gptkbp:complications |
important in diagnostics
|
| gptkbp:defense_mechanism |
trap and inhibit proteases
|
| gptkbp:ecological_role |
modulates immune response
implicated in chronic diseases |
| gptkbp:function |
serine protease inhibitor
|
| gptkbp:game_components |
extracellular space
|
| gptkbp:genetic_diversity |
highly conserved across species
increased risk of disease analyzed in population studies linked to susceptibility to diseases mapped to specific loci relevant for genetic counseling |
| gptkbp:has_transformation |
associated with different phenotypes
|
| https://www.w3.org/2000/01/rdf-schema#label |
A2 M gene
|
| gptkbp:intelligence |
found in many vertebrates
|
| gptkbp:interacts_with |
interacts with various proteins
|
| gptkbp:is_a_route_for |
involved in immune response
understood in disease mechanisms |
| gptkbp:is_analyzed_in |
used in various assays
investigated in laboratory settings |
| gptkbp:is_involved_in |
proteinase inhibition
|
| gptkbp:is_represented_in |
liver
upregulated in inflammation |
| gptkbp:is_tested_for |
available for genetic testing
used as a potential biomarker |
| gptkbp:located_in |
human chromosome 12
|
| gptkbp:nutritional_value |
involved in tissue repair
contains multiple domains found in blood plasma serpin superfamily inhibits various proteases |
| gptkbp:promoter |
gptkb:A2_M
gptkb:chemical_compound regulated by various factors serpin family |
| gptkbp:regulatory_compliance |
affected by cytokines
|
| gptkbp:related_to |
gptkb:psychologist
cancer progression |
| gptkbp:research |
binding activity
|
| gptkbp:research_areas |
target for drug development
explored for therapeutic interventions |
| gptkbp:research_focus |
target for genetic studies
|
| gptkbp:seed_dispersal |
protein-coding gene
|
| gptkbp:social_responsibility |
gptkb:psychologist
|