|
gptkbp:instanceOf
|
gptkb:protein
|
|
gptkbp:alternativeName
|
gptkb:C3_and_C4_binding_protein
gptkb:Pregnancy_zone_protein
gptkb:Sentrin
|
|
gptkbp:associatedWith
|
gptkb:Alzheimer's_disease
nephrotic syndrome
|
|
gptkbp:category
|
gptkb:protein
protease inhibitor
acute phase protein
|
|
gptkbp:discoveredBy
|
gptkb:Heinrich_Schultze
|
|
gptkbp:discoveredIn
|
1862
|
|
gptkbp:foundIn
|
gptkb:human
other mammals
|
|
gptkbp:fullName
|
gptkb:Alpha-2-macroglobulin
|
|
gptkbp:function
|
protease inhibitor
inhibits a broad spectrum of proteases
|
|
gptkbp:gene
|
gptkb:A2M
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
A2M
|
|
gptkbp:inhibitedBy
|
gptkb:thrombin
gptkb:trypsin
collagenase
plasmin
other endopeptidases
|
|
gptkbp:locatedOnChromosome
|
gptkb:chromosome_12p13.31
|
|
gptkbp:location
|
gptkb:plasma
|
|
gptkbp:medicalUse
|
biomarker for liver function
biomarker for nephrotic syndrome
|
|
gptkbp:molecularWeight
|
720 kDa (tetramer)
|
|
gptkbp:mutationAssociatedWith
|
gptkb:Alzheimer's_disease
prostate cancer
|
|
gptkbp:OMIM
|
103950
|
|
gptkbp:presentIn
|
blood plasma
|
|
gptkbp:structure
|
tetramer
|
|
gptkbp:synthesisType
|
liver
|
|
gptkbp:UniProtID
|
P01023
|
|
gptkbp:bfsParent
|
gptkb:Clustal
gptkb:Monsters_vs._Aliens_(video_game)
|
|
gptkbp:bfsLayer
|
6
|