|
gptkbp:instanceOf
|
gptkb:chemical_compound
|
|
gptkbp:appearance
|
yellow to orange crystalline powder
|
|
gptkbp:approvalYear
|
1978 (FDA)
|
|
gptkbp:ATCCode
|
L01XA01
|
|
gptkbp:CASNumber
|
gptkb:12629-01-5
|
|
gptkbp:drugClass
|
antineoplastic agent
|
|
gptkbp:hasDiscoverer
|
gptkb:Barnett_Rosenberg
|
|
gptkbp:hasInChIKey
|
KURNBZPLTSTZSP-UHFFFAOYSA-L
|
|
gptkbp:hasMolecularFormula
|
Cl2H6N2Pt
|
|
gptkbp:hasSMILES
|
N.N.Cl[Pt](Cl)N
|
|
gptkbp:hasTherapeuticUse
|
gptkb:cancer
testicular cancer
bladder cancer
|
|
gptkbp:hasUNII
|
Q20Q21Q62J
|
|
gptkbp:hasYearOfDiscovery
|
1965
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
12629-01-5
|
|
gptkbp:IUPACName
|
gptkb:cis-diamminedichloroplatinum(II)
|
|
gptkbp:legalStatus
|
prescription only
|
|
gptkbp:mechanismOfAction
|
DNA crosslinking
|
|
gptkbp:meltingPoint
|
270 °C (decomposes)
|
|
gptkbp:molecularWeight
|
300.05 g/mol
|
|
gptkbp:name
|
gptkb:cisplatin
|
|
gptkbp:PubChem_CID
|
DB00515
5702198
CHEMBL11359
|
|
gptkbp:routeOfAdministration
|
intravenous
|
|
gptkbp:solubility
|
2.53 g/L (at 25 °C)
|
|
gptkbp:synonym
|
gptkb:cis-diamminedichloroplatinum(II)
Platinol
cisplatinum
|
|
gptkbp:toxicity
|
nausea
vomiting
nephrotoxicity
neurotoxicity
ototoxicity
myelosuppression
|
|
gptkbp:bfsParent
|
gptkb:Humatrope
gptkb:H01AC01
gptkb:somatropin
|
|
gptkbp:bfsLayer
|
7
|