Statements (70)
| Predicate | Object |
|---|---|
| gptkbp:instance_of |
gptkb:protein
|
| gptkbp:associated_with |
gptkb:peripheral_artery_disease
gptkb:hospital gptkb:hemophilia_A gptkb:von_Willebrand_disease gptkb:deep_vein_thrombosis cardiovascular diseases thrombosis venous thromboembolism autoimmune disorders surgery complications cancer-related coagulopathy |
| gptkbp:clinical_trial |
diagnostic marker for bleeding disorders
|
| gptkbp:combatants |
platelets
factor VIII |
| gptkbp:discovered_by |
gptkb:Erik_von_Willebrand
|
| gptkbp:function |
mediates platelet adhesion
|
| gptkbp:has_weakness |
bleeding disorders
|
| https://www.w3.org/2000/01/rdf-schema#label |
von Willebrand factor
|
| gptkbp:increased |
gptkb:Company
stress inflammation obesity pregnancy smoking chronic kidney disease atherosclerosis chronic liver disease chronic inflammatory diseases |
| gptkbp:influences |
wound healing
blood pressure angiogenesis vascular permeability coagulation cascade thrombin generation endothelial function thrombus formation fibrin clot stability platelet lifespan tissue factor expression |
| gptkbp:interacts_with |
gptkb:skincare_product
|
| gptkbp:is_found_in |
blood plasma
endothelial Weibel-Palade bodies |
| gptkbp:is_involved_in |
gptkb:cerebral_venous_sinus_thrombosis
thromboembolic events ischemic stroke hemostasis pulmonary embolism vascular biology blood coagulation vascular repair arterial thrombosis microvascular thrombosis platelet plug formation thrombus resolution |
| gptkbp:measures |
von Willebrand factor antigen test
|
| gptkbp:produced_by |
endothelial cells
|
| gptkbp:promoter |
VWF
|
| gptkbp:reduces |
liver disease
sepsis hypothyroidism thrombocytopenia anticoagulant therapy antiplatelet therapy acute liver failure hypofibrinogenemia von Willebrand disease type 1 |
| gptkbp:role |
platelet aggregation
|
| gptkbp:bfsParent |
gptkb:von_Willebrand_disease
|
| gptkbp:bfsLayer |
4
|