Statements (27)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:protein
|
| gptkbp:alternativeName |
gptkb:Factor_VIII-related_antigen
gptkb:VWF |
| gptkbp:associatedWith |
gptkb:von_Willebrand_disease
|
| gptkbp:binds |
gptkb:collagen
gptkb:platelet_glycoprotein_Ib factor VIII |
| gptkbp:clinicalTrialPhase |
VWF antigen assay
ristocetin cofactor activity |
| gptkbp:deficiencyCauses |
bleeding tendency
|
| gptkbp:discoveredBy |
gptkb:Erik_Adolf_von_Willebrand
|
| gptkbp:encodedBy |
gptkb:VWF_gene
|
| gptkbp:foundIn |
blood plasma
|
| gptkbp:function |
binds to factor VIII
mediates platelet adhesion |
| gptkbp:halfLife |
8-12 hours
|
| gptkbp:locatedOnChromosome |
12p13.3
|
| gptkbp:location |
gptkb:megakaryocytes
endothelial cells |
| gptkbp:molecularWeight |
~270 kDa (monomer)
|
| gptkbp:releasedFromPrison |
gptkb:Weibel-Palade_bodies
alpha granules of platelets |
| gptkbp:role |
hemostasis
|
| gptkbp:structure |
multimeric protein
|
| gptkbp:bfsParent |
gptkb:Palade_bodies
|
| gptkbp:bfsLayer |
6
|
| http://www.w3.org/2000/01/rdf-schema#label |
von Willebrand factor
|