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gptkbp:instanceOf
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gptkb:disease
genetic disorder
bleeding disorder
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gptkbp:affects
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blood clotting
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gptkbp:causedBy
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deficiency of von Willebrand factor
dysfunction of von Willebrand factor
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gptkbp:complication
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gptkb:anemia
gastrointestinal bleeding
joint bleeding
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gptkbp:diagnosedBy
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gptkb:factor_VIII_activity_test
gptkb:ristocetin_cofactor_activity_test
gptkb:von_Willebrand_factor_antigen_test
blood tests
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gptkbp:differentialDiagnosis
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gptkb:platelet_function_disorders
gptkb:hemophilia_A
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gptkbp:field
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gptkb:medicine
genetics
hematology
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gptkbp:firstDescribed
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1926
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https://www.w3.org/2000/01/rdf-schema#label
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von Willebrand disease
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gptkbp:ICD-10_code
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gptkb:D68.0
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gptkbp:inheritance
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autosomal dominant
autosomal recessive
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gptkbp:MeSH_ID
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gptkb:D014842
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gptkbp:namedAfter
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gptkb:Erik_Adolf_von_Willebrand
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gptkbp:OMIM
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193400
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gptkbp:prevalence
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most common inherited bleeding disorder
affects up to 1% of the population
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gptkbp:riskFactor
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gptkb:blood_type_O
family history
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gptkbp:symptom
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easy bruising
frequent nosebleeds
heavy menstrual bleeding
excessive bleeding after injury
prolonged bleeding after surgery
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gptkbp:treatment
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gptkb:desmopressin
gptkb:antifibrinolytic_drugs
gptkb:von_Willebrand_factor_concentrates
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gptkbp:type
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Type 1
Type 2
Type 3
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gptkbp:Type_2_subtypes
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gptkb:2N
2A
2B
2M
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gptkbp:bfsParent
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gptkb:hemophilia_A
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gptkbp:bfsLayer
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5
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