von Willebrand disease

GPTKB entity

Statements (56)
Predicate Object
gptkbp:instance_of gptkb:Genetics
gptkbp:affects blood clotting
gptkbp:associated_with gptkb:Fuchsia
gptkbp:can_cause gptkb:anemia
fatigue
pain
gptkbp:can_lead_to gastrointestinal bleeding
joint problems
heavy menstrual bleeding
gptkbp:caused_by deficiency of von Willebrand factor
gptkbp:diagnosis gptkb:hemophilia_A
blood tests
thrombocytopenia
other bleeding disorders
gptkbp:difficulty_levels gptkb:Type_3
gptkbp:first_described_by gptkb:Erik_von_Willebrand
gptkbp:has_achieved gptkb:surgery
injury
pregnancy
https://www.w3.org/2000/01/rdf-schema#label von Willebrand disease
gptkbp:inherits_from autosomal dominant
gptkbp:is gptkb:hemophilia_B
acquired bleeding disorder
thrombotic disorder
gptkbp:is_common_in both genders
all ethnic groups
gptkbp:is_less_severe_in Type 1
Type 2
gptkbp:is_monitored_by treatment response
factor levels
bleeding episodes
gptkbp:is_recognized_by genetic testing
ristocetin cofactor assay
von Willebrand factor activity test
gptkbp:is_related_to gptkb:von_Willebrand_factor
coagulation cascade
platelet function
gptkbp:is_studied_in clinical trials
gptkbp:managed_by hematologist
gptkbp:prevalence 1% of the population
gptkbp:screenings family history
clinical evaluation
laboratory tests
gptkbp:symptoms easy bruising
excessive bleeding
prolonged bleeding after injury
gptkbp:treatment platelet transfusions
desmopressin
factor replacement therapy
hormonal therapy
antifibrinolytics
gptkbp:type_of gptkb:Type_3
Type 1
Type 2
gptkbp:bfsParent gptkb:Dog
gptkbp:bfsLayer 4