tyrosine-protein phosphatase non-receptor type 11
GPTKB entity
Statements (33)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:protein
|
| gptkbp:alternativeName |
gptkb:PTP-1D
gptkb:PTP2C gptkb:SHP-2 PTP-2C PTP1D |
| gptkbp:domain |
gptkb:protein_tyrosine_phosphatase_domain
SH2 domain |
| gptkbp:encodedBy |
gptkb:PTPN11
|
| gptkbp:foundIn |
gptkb:Homo_sapiens
|
| gptkbp:function |
signal transduction
protein tyrosine phosphatase activity |
| https://www.w3.org/2000/01/rdf-schema#label |
tyrosine-protein phosphatase non-receptor type 11
|
| gptkbp:involvedIn |
gptkb:RAS/MAPK_signaling_pathway
cell differentiation cell growth cell migration cellular response to growth factor stimulus |
| gptkbp:location |
gptkb:nucleus
gptkb:cytoplasm gptkb:chromosome_12q24 |
| gptkbp:molecularWeight |
68 kDa
|
| gptkbp:mutationAssociatedWith |
gptkb:LEOPARD_syndrome
gptkb:juvenile_myelomonocytic_leukemia gptkb:Noonan_syndrome |
| gptkbp:OMIM |
176876
|
| gptkbp:regulates |
apoptosis
cell proliferation cell signaling hematopoiesis |
| gptkbp:UniProtID |
Q06124
|
| gptkbp:bfsParent |
gptkb:PTPN11_gene
|
| gptkbp:bfsLayer |
7
|