Statements (23)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:CRISPR-Cas_system
|
| gptkbp:application |
genome editing
gene activation gene knockout gene repression |
| gptkbp:component |
gptkb:Cas9_protein
gptkb:crRNA gptkb:tracrRNA |
| gptkbp:contains |
gptkb:Cas9_protein
|
| gptkbp:discoveredBy |
gptkb:Emmanuelle_Charpentier
gptkb:Jennifer_Doudna |
| gptkbp:firstDescribed |
2012
|
| gptkbp:foundIn |
gptkb:Bacteria
archaea |
| https://www.w3.org/2000/01/rdf-schema#label |
type II CRISPR system
|
| gptkbp:mechanismOfAction |
cleaves double-stranded DNA
uses single guide RNA |
| gptkbp:requires |
PAM sequence
|
| gptkbp:subclassOf |
gptkb:CRISPR-Cas_system
|
| gptkbp:usedIn |
gptkb:biotechnology
gptkb:medicine |
| gptkbp:bfsParent |
gptkb:type_V_CRISPR_system
|
| gptkbp:bfsLayer |
8
|