Statements (29)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:protein
|
| gptkbp:alternativeSplicing |
yes
|
| gptkbp:discoveredBy |
William Astbury
|
| gptkbp:discoveredIn |
1930s
|
| gptkbp:foundIn |
gptkb:skeletal_muscle
|
| gptkbp:function |
regulation of muscle contraction
|
| gptkbp:gene |
gptkb:TPM3
TPM1 TPM2 TPM4 |
| gptkbp:hasIsoform |
multiple
|
| https://www.w3.org/2000/01/rdf-schema#label |
tropomyosin
|
| gptkbp:interactsWith |
gptkb:actin
gptkb:troponin |
| gptkbp:location |
cytoskeleton
sarcomere |
| gptkbp:molecularWeight |
~32 kDa
|
| gptkbp:mutationAssociatedWith |
cardiomyopathy
nemaline myopathy |
| gptkbp:presentIn |
invertebrates
vertebrates eukaryotes |
| gptkbp:role |
muscle contraction regulation
stabilization of actin filaments |
| gptkbp:structure |
coiled-coil
|
| gptkbp:subunit |
thin filament
|
| gptkbp:bfsParent |
gptkb:actin
gptkb:sliding_filament_theory |
| gptkbp:bfsLayer |
7
|