|
gptkbp:instanceOf
|
scientific theory
|
|
gptkbp:appliesTo
|
gptkb:skeletal_muscle
cardiac muscle
|
|
gptkbp:category
|
biophysics
muscle physiology
|
|
gptkbp:component
|
gptkb:M_line
gptkb:H_zone
gptkb:Z_line
A band
I band
sarcomere
actin filament
myosin filament
|
|
gptkbp:contrastsWith
|
folding filament theory
|
|
gptkbp:describes
|
muscle contraction
|
|
gptkbp:evidence
|
X-ray diffraction
electron microscopy
|
|
gptkbp:explains
|
interaction of actin and myosin filaments
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
sliding filament theory
|
|
gptkbp:influenced
|
modern muscle physiology
|
|
gptkbp:involves
|
gptkb:tropomyosin
gptkb:troponin
|
|
gptkbp:mechanismOfAction
|
ATP hydrolysis
cross-bridge cycling
myosin heads bind to actin
|
|
gptkbp:proposedBy
|
gptkb:Andrew_Huxley
gptkb:Jean_Hanson
gptkb:Rolf_Niedergerke
gptkb:Hugh_Huxley
|
|
gptkbp:publishedIn
|
gptkb:Nature
gptkb:Proceedings_of_the_Royal_Society_B
|
|
gptkbp:requires
|
gptkb:ATP
calcium ions
|
|
gptkbp:result
|
muscle fiber contracts
sarcomere shortens
|
|
gptkbp:yearProposed
|
1954
|
|
gptkbp:bfsParent
|
gptkb:Hugh_E._Huxley
gptkb:Hugh_Huxley
|
|
gptkbp:bfsLayer
|
6
|