toxic epidermal necrolysis

GPTKB entity

Predicate	Object
gptkbp:instanceOf	gptkb:disease gptkb:skin_disorder
gptkbp:affects	gptkb:skin mucous membranes
gptkbp:age	all ages
gptkbp:alsoKnownAs	TEN
gptkbp:causedBy	gptkb:adverse_drug_reaction infection
gptkbp:characterizedBy	mucous membrane involvement widespread skin detachment
gptkbp:commonHealthIssues	gptkb:NSAIDs allopurinol anticonvulsants sulfonamides
gptkbp:complication	sepsis multi-organ failure
gptkbp:diagnosedBy	clinical examination skin biopsy
gptkbp:differentialDiagnosis	gptkb:pemphigus_vulgaris gptkb:erythema_multiforme gptkb:staphylococcal_scalded_skin_syndrome
gptkbp:firstDescribed	1956
gptkbp:hasEpidemiology	rare
gptkbp:ICD-10_code	L51.2
gptkbp:mortalityRate	high
gptkbp:pathology	keratinocyte apoptosis
gptkbp:percentageBodySurfaceArea	>30%
gptkbp:prognosis	poor
gptkbp:relatedTo	gptkb:Stevens-Johnson_syndrome
gptkbp:riskFactor	immunosuppression HIV infection
gptkbp:sex	both sexes
gptkbp:symptom	fever conjunctivitis blistering skin pain
gptkbp:treatment	gptkb:cyclosporine supportive care corticosteroids IV immunoglobulin
gptkbp:bfsParent	gptkb:Stevens–Johnson_syndrome
gptkbp:bfsLayer	6
https://www.w3.org/2000/01/rdf-schema#label	toxic epidermal necrolysis