pemphigus vulgaris

GPTKB entity

Statements (38)
Predicate Object
gptkbp:instanceOf gptkb:skin
autoimmune disease
gptkbp:affects gptkb:skin
mucous membranes
gptkbp:antibodyTarget gptkb:desmoglein_1
gptkb:desmoglein_3
gptkbp:causedBy autoantibodies
gptkbp:complication infection
dehydration
gptkbp:diagnosedBy gptkb:ELISA
biopsy
direct immunofluorescence
gptkbp:differentialDiagnosis gptkb:bullous_pemphigoid
gptkb:mucous_membrane_pemphigoid
gptkb:lichen_planus
gptkbp:field immunology
dermatology
gptkbp:firstDescribed 1788
https://www.w3.org/2000/01/rdf-schema#label pemphigus vulgaris
gptkbp:ICD-10_code L10.0
gptkbp:MeSH_ID D010392
gptkbp:mortalityRate potentially fatal if untreated
gptkbp:namedFor gptkb:Willan
gptkbp:OMIM 169610
gptkbp:onset middle-aged adults
gptkbp:prevalence rare
gptkbp:riskFactor genetic predisposition
certain HLA types
gptkbp:symptom blisters
painful sores
oral ulcers
erosions
gptkbp:treatment gptkb:rituximab
corticosteroids
immunosuppressants
gptkbp:bfsParent gptkb:rituximab
gptkb:Chris_Stein
gptkbp:bfsLayer 6