pemphigus vulgaris

GPTKB entity

Statements (44)
Predicate Object
gptkbp:instance_of gptkb:healthcare_organization
gptkbp:affects gptkb:skincare_product
mucous membranes
gptkbp:associated_with gptkb:Insurance_Company
thymoma
gptkbp:caused_by autoimmune response
gptkbp:clinical_trial skin lesions
oral lesions
Nikolsky sign positive
gptkbp:complications gptkb:healthcare_organization
malnutrition
dehydration
gptkbp:current_use gptkb:pemphigus_foliaceus
gptkbp:first_described_by 1930s
gptkbp:historical_significance first autoimmune blistering disease described
influenced dermatology research
https://www.w3.org/2000/01/rdf-schema#label pemphigus vulgaris
gptkbp:is_a_route_for antibodies against desmogleins
loss of cell adhesion
gptkbp:is_popular_in rare
gptkbp:public_awareness gptkb:Pemphigus_Awareness_Month
September
gptkbp:research_focus biomarkers
genetic studies
new therapies
understanding pathogenesis
gptkbp:risk_factor HLA-DQ B1*03:01
HLA-DR B1*04:02
gptkbp:scholarships educational resources available
support groups available
gptkbp:social_responsibility variable
biopsy
can be life-threatening
more common in women
direct immunofluorescence
typically diagnosed in middle age
gptkbp:symptoms blisters
painful sores
gptkbp:treatment corticosteroids
immunosuppressants
chronic condition
remission possible
gptkbp:bfsParent gptkb:Rituxan
gptkbp:bfsLayer 4