Statements (22)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:gene
|
| gptkbp:alternativeName |
DNA topoisomerase II alpha subunit
TOP2 |
| gptkbp:associatedWith |
gptkb:cancer
|
| gptkbp:encodes |
DNA topoisomerase II alpha
|
| gptkbp:Entrez_Gene_ID |
7153
ENSG00000131747 |
| gptkbp:expressedIn |
proliferating cells
|
| gptkbp:function |
involved in DNA replication
controls topological states of DNA during transcription involved in chromosome segregation |
| https://www.w3.org/2000/01/rdf-schema#label |
topoisomerase II alpha gene
|
| gptkbp:locatedOnChromosome |
gptkb:chromosome_17
17q21-q22 |
| gptkbp:mutationAssociatedWith |
drug resistance
|
| gptkbp:organism |
gptkb:Homo_sapiens
|
| gptkbp:orthologInMouse |
Top2a
|
| gptkbp:symbol |
TOP2A
|
| gptkbp:target |
anticancer drugs
|
| gptkbp:UniProtID |
P11388
|
| gptkbp:bfsParent |
gptkb:B-Myb
|
| gptkbp:bfsLayer |
8
|