Statements (29)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:enzyme
|
| gptkbp:alternativeName |
PD-ECGF
deoxyribosyltransferase platelet-derived endothelial cell growth factor |
| gptkbp:associatedWith |
Mitochondrial neurogastrointestinal encephalopathy syndrome
|
| gptkbp:catalyzes |
thymidine + phosphate ⇌ thymine + 2-deoxy-α-D-ribose 1-phosphate
|
| gptkbp:cofactor |
none
|
| gptkbp:discoveredBy |
1954
|
| gptkbp:EC_number |
2.4.2.4
|
| gptkbp:expressedIn |
platelets
endothelial cells |
| gptkbp:foundIn |
gptkb:Homo_sapiens
gptkb:Bacteria |
| gptkbp:function |
pyrimidine nucleoside metabolism
|
| gptkbp:gene |
TYMP
|
| gptkbp:GO_term |
GO:0009030
|
| https://www.w3.org/2000/01/rdf-schema#label |
thymidine phosphorylase
|
| gptkbp:inhibitedBy |
tipiracil
5-iodouracil |
| gptkbp:locatedOnChromosome |
22q13.33 (human)
|
| gptkbp:molecularWeight |
~50 kDa (monomer)
|
| gptkbp:PDB |
1UOU
|
| gptkbp:role |
angiogenesis
nucleotide salvage pathway |
| gptkbp:significance |
target for anticancer drugs
|
| gptkbp:structure |
homodimer
|
| gptkbp:UniProtID |
P19971
|
| gptkbp:bfsParent |
gptkb:T5D
|
| gptkbp:bfsLayer |
8
|