Statements (23)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:enzyme
|
| gptkbp:biologicalProcess |
nucleotide metabolism
transferase activity |
| gptkbp:catalyzes |
phosphorylation of thymidine to thymidine monophosphate
|
| gptkbp:chromosome_location_(human_TK1) |
gptkb:17q23.2
|
| gptkbp:cofactor |
gptkb:ATP
|
| gptkbp:EC_number |
2.7.1.21
|
| gptkbp:foundIn |
viruses
prokaryotes eukaryotes |
| gptkbp:gene |
TK1
|
| gptkbp:gene_symbol_(herpes_simplex_virus) |
UL23
|
| https://www.w3.org/2000/01/rdf-schema#label |
thymidine kinase
|
| gptkbp:inhibitedBy |
gptkb:acyclovir
gptkb:ganciclovir |
| gptkbp:product |
thymidine monophosphate
|
| gptkbp:structure |
homodimer
|
| gptkbp:substrate |
thymidine
|
| gptkbp:used_in |
antiviral drug activation
suicide gene therapy |
| gptkbp:usedFor |
cell proliferation marker
|
| gptkbp:bfsParent |
gptkb:E2F_transcription_factor_1
|
| gptkbp:bfsLayer |
8
|