ganciclovir

GPTKB entity

Statements (32)
Predicate Object
gptkbp:instanceOf antiviral drug
gptkbp:administeredBy immunocompromised patients
gptkbp:approvedBy 1989
gptkbp:ATCCode J05AB06
gptkbp:CASNumber 82410-32-0
gptkbp:contraindication severe neutropenia
hypersensitivity to ganciclovir
gptkbp:discoveredBy gptkb:Syntex
gptkbp:drugClass antiviral
gptkbp:eliminationHalfLife 2.5-4 hours
gptkbp:hasMolecularFormula C9H13N5O4
https://www.w3.org/2000/01/rdf-schema#label ganciclovir
gptkbp:legalStatus prescription only
gptkbp:mechanismOfAction inhibits viral DNA polymerase
gptkbp:metabolism liver
gptkbp:pregnancyCategory C (US)
gptkbp:prodrugOf gptkb:valganciclovir
gptkbp:routeOfAdministration oral
intravenous
gptkbp:sideEffect gptkb:anemia
fever
rash
neutropenia
thrombocytopenia
renal toxicity
gptkbp:synonym Cytovene
DHPG
gptkbp:usedFor gptkb:cytomegalovirus_infection
herpes simplex virus infection
varicella zoster virus infection
gptkbp:bfsParent gptkb:virus
gptkbp:bfsLayer 5